PARKINSON'S; OR NOT?
The purpose here is an education/ therefore patient and doctor, etc: need NOT be known. The media or any other; given no permission to guess.
THE REALITY discussed is: doctors are not "gods/ they can be wrong". The intent is NOT to discredit or demean any facility or person: rather evidence is considered. The consequence of drug use is to be evaluated by the reader, as it affects their own life. The definitions of all related decisions on both sides of the issues and drugs are serious, particularly for the patient: that means a fight over what is best, cannot be simple. Life comes first, but as with any other fight to decide what is true: once "the best you can do/ has been done" everyone, including me must surrender to "we must hope for the best" from this moment on. We/ I/ you; ain't god either. Even if correct, each one has their own decision to make. If its not your own life/ then once you have done the best you can: this is over, apart from being a friend, if you can. When those who can make the decision, after all the evidence is realistically exposed/ do make the decision "as educated as possible". That is, "the end of the work/ fight", and what we/ you/ or I can do. Legal issues over "this is the best decision we honestly believed we could or did make"; do not exist. You cannot fix "a broken or dead life" with money. Because the reality of any disease is: if we cannot do this ourselves/ then somebody has to make the decision for us; and that means we do accept the consequences, if it was realistically, honest and true for life. Even if wrong. In the harsh realities of life, there is no wrong or right/ only "the best we did do". And each will, "live with that knowledge/ each will understand: this was my or our respect, given to you". Wrong or right is irrelevant, if you did do your best. That is just how it is; like it or not; we all die. We are all subjected to, or by our own reality; to life.
Having requested your attention in the matter of , and those involved who have deliberately chosen to harm her. The question is: do you care?
The evidence: Of note, as proven by attending neurologist. Under whose care she did not do well. What is important and of primary concern at this moment is established in his report 11/27/ 2012 1:50 office visit MRN:
under care: the dosage for quetiapine page 2: was 12.5 mg once daily. According to the list of medications provided by the nursing staff 12/27/13 resident 2212 under the care of the dosage for quetiapine is expected to be, 12.5 mg once daily.
the dosage established by the pharmacy report/: 11/28/12.
Thereby given to the patient or stolen under the patient's name: from pharmacy lists quetiapine 25 mg 11/ 06/ 2012 quantity 45
and pharmacy lists quetiapine 25 mg 11/ 28/ 12 quantity 45 the period of time between the delivery and usage of quetiapine equals 22 days, or just over 2 pills a day totaling a delivery of the medicine at 50 mg instead of the prescribed 12.5.
AN INCREASE OF 400 PERCENT over and above "doctors orders".
Her prescription drug summary from quetiapine for 8/ 20/ 12 was 25mg /quantity 30; then again at 9/ 10/ 12 25 mg / quantity 45. Days between are 22/ dosage 25mg: establishing pills received are more than one a day(not quite one and one half a day) at 25 mg/ not 12.5 I do not have the October report. Nor do I have the doctor prescription, indicating dosage, for that period of time.
I do not yet have the December report. The patient's personal privacy IS ENACTED/ and demanded for her peace of mind, and ability to tolerate this situation.
Quetiapine; is a very powerful "MIND-MELTING/ we can control you" drug. Listed purpose: for the control of manic depression Therefore the question is why? The question is where is the medicine paid for going? What is the discrepance established between what was prescribed and what was received from the pharmacy? The reality returns as felony assault and battery; as the beginning of this discussion: if it turns out that is beginning over medicated; as is nearly certain due to the extreme poor posture that she presented over a period of weeks, and other factors that clearly and dramatically changed her ability to live with dignity.
During the last two months, the patient demonstrated ALL THE SYMPTOMS LISTED: "take her to the emergency room (difficulty breathing; swelling of the face; lips, tongue, or throat)". She complained very clearly: her head was over ninety degrees from upright on her chest, "because she couldn't breathe" any other way. Face obviously swelled. And many more of the symptoms listed. She began to have tremors on Christmas day. Following the previous letter to this nursing home from me; I returned two days after its receipt by the facility to find an entirely new ; after roughly two months of continued deterioration/ she looked better than the day she moved in, two days later she was again experiencing difficulties, but the extreme poor posture remains gone today. However I picked her up at 9:30 am this morning and she was near comatose/ when finally responding, she was unable to open her eyes for fifteen minutes and complained of "heavy legs" and unable to move, to any degree after opening her eyes; for at least 30 minutes more. Af
During that time, and on previous occasions the patient states repeatedly that dr franzen would not acknowledge her whatsoever until this last week (now being confronted). Instead of attending to her, at any time. Her statement is: any time she saw him in the nursing home he would immediately look away/ say nothing/ and disappear.
The question is why? When according to the drug label side effects, "she should have been taken to the emergency room".
Criminal conduct and its appropriate punishment is directed according to damage done/ or intended to be done. Therefore the question is: what is, 50 mg of quetiapine a day; intended to do? Where did it go? The director states it was credited, thereby recognized; but it still leaves a double dose of pills instead of 4 times as much? Who prescribed it? Who refused to acknowledge: "we have lots of pills left over"/ wrong strength/ wrong prescription? Cut in half to obtain the 12.5 mg dosage: 45 pills equals enough medicine for 90 days. The question is how long has this been going on: what was the prescription during that time. Over at least a period of a month, and where did those pills go? We bought and paid for them. The pharmacy says it was delivered. Yet none have found a cause over a lengthy period of time to discover THIS IS WRONG. Somebody is responsible. Somebody has had access to very powerful mind altering drugs that can do a great deal of harm. In a nursing home environment it is very easy to refrain from giving one patient medicine and adding to the next: if you want too. Not saying that happened, but has had a dramatic and rapid deterioration since entering here. AN INVESTIGATION IS REQUIRED. A reality check at the nursing home is required to access and understand how it is that this patient presented all the symptoms necessary for an emergency room visit: YET NO ONE DID ANYTHING, but let her suffer!
These are questions required of the police or the nursing home to investigate. And it clearly should be done together; until the matter is resolved. It is possible, therefore stated: the problem could be within pharmacy/ but that is unlikely given the presentation of symptoms by of a clear drug overdose "to any trained eye". The excuse that 25 mg pills were ordered to then be broken in two; treads water until you realized how many pills are involved, and the length of time proven true. Where is the accounting for those extra pills? It may be as simple as "doctors orders"/ or not.
Dosage for schizophrenia begins at 50mg a day same for bi-polar or depression.
Precautions
Quetiapine is not approved by the FDA for use in the treatment of behavioral disorders in elderly patients with dementia. Collective data from 17 placebo-controlled clinical studies (n=5106) involving the use of atypical antipsychotic agents, including quetiapine, for the treatment of behavioral disorders in the elderly patient with dementia showed a risk of death 1.6 to 1.7 times greater in the drug- treated patient than in the placebo- treated patient. The average length of duration for the trials was 10 weeks with the cause of death in the majority of cases, though not all, reported as either cardiovascular (e.g., heart failure, sudden death) or infectious (e.g., pneumonia) in nature.
Some side effects of quetiapine may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
For the Consumer
Applies to quetiapine: oral tablet, oral tablet extended release
Get emergency medical help if you have any of these signs of an allergic reaction while taking quetiapine: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.
Stop using quetiapine and call your doctor at once if you have a serious side effect such as:
very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors;
feeling like you might pass out;
jerky muscle movements you cannot control, trouble swallowing, problems with speech;
tremors, or restless muscle movements in your eyes, tongue, jaw, neck, arms, or legs;
mask-like appearance of the face, trouble swallowing, problems with speech;
blurred vision, eye pain, or seeing halos around lights;
increased thirst and urination, excessive hunger, fruity breath odor, weakness, nausea and vomiting; or
fever, chills, body aches, flu symptoms, white patches or sores inside your mouth or on your lips.
Less serious side effects of quetiapine may include:
dizziness, drowsiness, tired feeling;
dry mouth, sore throat;
stomach pain, upset stomach, nausea, vomiting, constipation;
breast swelling or discharge;
missed menstrual periods; or
increased appetite, weight gain.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
For Healthcare Professionals
Applies to quetiapine: oral tablet, oral tablet extended release
Nervous system
Lower (worse) baseline scores predicted greater cognitive improvement. Change In cognitive performance was weakly related to change in symptom scores.
Nervous system side effects have included agitation (20%), somnolence (sleepy) (18%), dizziness (11%), tremor (8%), and anxiety (4%). Hypertonia, dysarthria (difficulty articulating words), abnormal dreams, dyskinesia (impairment of voluntary motion, resulting in fragmented or jerky motions (as in parkinson disease) , abnormal thinking, tardive dyskinesia, vertigo, involuntary movements, confusion, amnesia, hyperkinesia, increased libido (sex drive), in-coordination, abnormal gait, myoclonus (irregular involuntary contraction of muscles...functional disorder of controlling motoneurons), apathy, ataxia (an inability to coordinate voluntary muscular movements that is symptomatic of some nervous disorders), stupor, bruxism, hemiplegia (total or partial paralysis of one side of the body that results from disease or or injury to the motor centers of the brain), aphasia (loss or impairment of the power to use or comprehend words, resulting from brain damage), buccoglossal syndrome (Buccoglossal syndrome is another term for Tardive Diskinesia, an incurable disease which causes uncontrolled movements of the body), choreoathetosis (
irregular involuntary movements that may involve the face, neck, trunk, extremities, or respiratory muscles, giving an appearance of restlessness. The writhing movements may vary from subtle to wild and ballistic and are commonly associated with administration of levodopa in parkinsonism. Levodopa-induced involuntary movement (dyskinesia) occurs most commonly 1 to 3 hours after administration of the drug), delirium, decreased libido, neuralgia (acute pain), stuttering, akathisia,(Anxiety, restlessness and hyperkinesia qualify a person with this movement disorder. Causes, motor behavior and treatment of akathisia; Dystonia , muscle contraction (twists, kinks, poor posture of the body).
Disorders of behavior and thought disorder (depression, hostility, suicidal tendencies). ). dystonia, parkinsonism (nervous disorder that resembles parkinsons disease), and subdural hematoma (A subdural hematoma is a collection of blood outside the brain. Subdural hematomas are usually caused by severe head injuries. The bleeding and increased pressure on the brain from a subdural hematoma can be life-threatening. Some subdural hematomas stop and resolve spontaneously; others require surgical drainage.) have also been reported; however, causality has not been established. Two cases of neuroleptic (any of the powerful tranquilizers used to treat psychosis and believed to act by blocking dopamine nervous receptors) malignant (extremely bad) syndrome that may possibly have been related to quetiapine use have also been reported. One case of quetiapine associated restless leg syndrome has been reported.
We add to the effects of quetiapine with
mirapex pramipexole: may cause hallucinations (the sensation of hearing or seeing something that is not there) most commonly among elderly. Increased sexual urges. May cause drowsiness, falling asleep suddenly, even after feeling alert. Feeling short of breath; feeling week or tired. Tremors. Swelling in your face , lips, tongue or throat
Lasix (furosemide) can lead to profound diuresis with water and electrolyte depletion. Red pinpoint spots under your skin (lower legs).
Seroquel; increased risk of suicidal thinking
bisoprl: swelling in your hands or feet.
Quetiapine is not for the treatment of parkinsons/ but many receive it; because it controls people.
parkinsons is: "resting tremor; slowness of movement, and rigidity".
Many people also experience balance problems.
Typically, symptoms begin on one side of the body and migrate over time to the other side.
There is no objective test to make a definitive diagnosis/ so the rate of mis-diagnosis can be relatively high.
More pronounced symptoms----can result from the long term use of levodopa
parkinsons disease is one of several diseases categorized by clinicians as movement disorders.
If necessary, the dosage of carbidopa/levodopa 25-250 may be increased by 1/2 to 1 tablet every day or every other day to a maximum of 8 tablets per day (That equals: 200/ 2000) . Experience with total daily dosages of carbidopa greater than 200 mg is limited.
's dosage is prescribed by 11/27/12 as: 6 tablets at 50-200 daily bringing the total to carbidopa 300/ levodopa 1200. dosage 1/6/13: 2.5 tablets at 50-200 per day total 125/ 500
What are the possible side effects of carbidopa and levodopa (Atamet, Parcopa, Sinemet, Sinemet CR)?
You may notice that your sweat, urine, or saliva appears dark in color, such as red, brown, or black. This is not a harmful side effect, but it may cause staining of your clothes or bed sheets.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:
restless muscle movements in your eyes, tongue, jaw, or neck;
worsening of tremors...
Read All Potential Side Effects and See Pictures of Sinemet CR »
What are the precautions when taking carbidopa-levodopa sustained release (Sinemet CR)?
Before taking this medication, tell your doctor or pharmacist if you are allergic to carbidopa or levodopa; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: certain eye problem (narrow-angle glaucoma).
Before using this medication, tell your doctor or pharmacist your medical history, especially of: bleeding disorders, breathing problems (e.g., asthma, emphysema), certain eye problem (wide-angle glaucoma), heart or blood vessel problems (e.g., arrhythmias, heart attack, angina), kidney disease,...
Read All Potential Precautions of Sinemet CR »
dverse-Effects.org
All reports Drugs Illnesses Reactions mirapex
PARKINSON'S DISEASE
Event Date Manufacturer Drug Side Effects
2006-11-10 Merck Human Health Division Stromectol anaemia show
2006-11-10 Merck Human Health Division Stromectol anaemia show
2006-12-08 Novartis Pharmaceuticals Corp. Parlodel neuroleptic malignant syndrome show
2006-09-29 Glaxosmithkline Valtrex depressed level of consciousness, feeling abnormal show
2006-12-10 Glaxosmithkline Requip dizziness show
Boehringer Ingelheim Pharmaceuticals, Inc. Pramipexole Dihydrochloride neuroleptic malignant syndrome show
2006-10-27 Boehringer Ingelheim Pharmaceuticals, Inc. Sifrol abasia, asthenia show
2006-10-27 Boehringer Ingelheim Pharmaceuticals, Inc. Sifrol abasia, asthenia show
Eli Lilly And Company Teriparatide erythema, oedema peripheral show
2005-12-01 Pfizer Inc Cabaseril aortic valve incompetence, aortic valve sclerosis show
2006-11-18 Zelapar anaemia, drug interaction show
2006-12-04 Novartis Pharmaceuticals Corp. Metoprolol Succinate asthenia, fall show
2006-01-01 Eisai Inc. Zonegran abnormal behaviour, aggression show
2006-11-07 Eisai Inc. Zonegran back pain, inguinal hernia show
2006-12-18 Bristol Myers Squibb Company Sinemet suicide attempt show
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Data presented on this site are drawn from the U.S. Food and Drug Administration's Adverse Event Reporting System for the years 2007-2011.
THE QUESTION MOST IDENTIFIED BY THIS DISPLAY OF EVIDENCE IS: Is not the "cure"/ WORSE than the disease? At least for most.